
Why alcohol withdrawal is dangerous
Heavy chronic alcohol use causes the brain to upregulate excitatory neurotransmission to balance alcohol's depressant effect. When alcohol is suddenly removed, that excitatory system has no counterweight — producing tremor, anxiety, racing heart, dangerously high blood pressure, and in moderate-to-severe cases, withdrawal seizures and delirium tremens. DTs carry a mortality rate of 1–5% even with treatment, and substantially higher without.
- Tremor, sweats, tachycardia within 6–12 hours
- Seizure risk peaks at 24–48 hours
- Delirium tremens onset at 48–96 hours
- Untreated DT mortality can exceed 15%





